High Desert Heart Institute Study

ProArgi-9 Plus!

Located in Victorville, California, the High Desert Heart Institute has begun to attract national attention for it’s ground breaking heart disease study. If as expected, the data collected, continues to support the trends observed in the study, then the conclusions & convictions of Dr. J. Joseph Prendergast & Dr. Louis Ignarro (Nobel Prize winner in medicine for his discovery of l-Arginine), that heart disease can indeed be prevented & even reversed by a proper regimen of L-Arginine, will be further enhanced.

The following is an overview of this landmark, 90 day, human clinical study conducted at one of the most prestigious heart institutes in the United States. As new information becomes available, & the study is finally published, I will report it on this blog so as to be a central resource page for this important study.

General Overview

In early 2009, a 90 day human clinical study was conducted at the High Desert Heart Institute. The study included 35 congestive heart failure patients from the Congestive Heart Failure Unit at the institute. The study concluded in July 2009 with 33 patients. One of the patients dropped out because he received a new heart. The other patient dropped out because they were not able to remain compliant with the study’s protocols.

Each patient over the course of the 90 day study received rather extensive diagnostic testing which generated approximately 7000 points of data. The following is a partial list of tests used to generate the data:

Full Blood Panels (Including Fasting Lipid & Electrolytes)

Full Urine Panels


Two Forms Pulse Wave Analysis

C-Reactive Protein Levels

Vitamin D3 Levels

Ankle Brachial Index Testing (Using Ultra Sound Doppler)

CT Heart Scan

The patients chosen for the study had all reached a virtual point of no return, a maximum of their pharmacological & medical management system in place. Each patient was given 4 scoops of ProArgi-9 per day for 90 days. Each scoop contains 5 grams of Pharmaceutical grade L-Arginine as well as several other ingredients that support Nitric Oxide production & heart health.

It may be a little bit before the study will be completely ready for publication in the medical journals. The wheels of the medical community can grind slowly when it comes to these kind of publications.  However, Dr. Siva Arunasalam, who helped direct & supervise the study stated this:

There was nothing else for us to try, we had tried everything with these patients.  All patients showed a tremendous improvement in many, many objective data points that only can be attributed to ProArgi-9. . .”

Dr. Siva also made the following significant statement:

“. . . but what we ended up seeing was remarkable positive remodeling of the heart, positive pulmonary artery changes, pulmonary vascular changes in terms of pulmonary pressures, changes in the cardiac dimensions, changes in heart function. . .”

Due to the remarkable success of this study, the High Desert Heart Institute has formally implemented an L-Arginine protocol utilizing the ProArgi-9 Plus as part of their routine standard of care for all patients.

The Contributors

High Desert Heart Institute – This institute, with ties to Cedars Sinai Medical Center in L.A., is located in Victorville, California & provides primary care & heart disease services in an outpatient setting. This outpatient center provides all of the routine heart tests such as electrocardiography, event monitoring, Holter monitoring, and routine blood tests.  In the area of advanced diagnostic and therapeutic methods, this institute provides in-house echocardiography, vascular ultrasound, nuclear stress testing, pulmonary function testing as well as a variety of other important diagnostic modalities.  This is the first outpatient center in the High Desert area to provide EECP (Enhanced External Counter Pulsation) which is an important therapy for those patients with angina and heart failure.

Dr. Siva Arunasalam – Dr. Siva (as he prefers to be called) is the Founder and Director of the High Desert Heart Institute.   He authorized this study and paid for all the testing and patient care.  Dr. Siva completed his cardiology training at Cedars-Sinai Medical Center in Los Angeles.  He was recruited by St. Mary Regional Medical Center to bring advanced cardiac care technology to the High Desert area.  Initially the Institute started in a small office near the hospital but had explosive growth requiring a move to a larger facility.  Because of the excellent care and treatment patients receive, the Institute is in the process of building an even larger facility on Hesperia Road so that it can better care for and service patients as well as incorporate more specialists into their operation.


Click Here For an Audio Clip of Dr. Siva & Dan Austin as They Discuss This Landmark Clinical Study


Dan Austin, RN – Dan is the director of the Congestive Heart Failure Unit at the High Desert Heart Institute.  He helped design this study and was the RN in charge of every patient in this study.

ProArgi-9 Plus – This is the nutritional supplement used in this groundbreaking study.  This product is designed by Dr. J. Joseph Prendergast and manufactured by Synergy WorldWide.  It contains 5 grams of pharmaceutical grade L-Arginine plus several other ingredients that support Nitric Oxide production and heart health.

Dr. J. Joseph Prendergast – Dr. Joe (as he prefers to call himself) is Board Certified in Internal Medicine, Endocrinology and Metabolism and has a very large patient population at the Endocrine Metabolic Medical Center in Palo Alto California.  Dr. Joe is a pioneer in the potential of L-Arginine (the precursor for Nitric Oxide) to dramatically affect cardiovascular health.  He is the product designer of the nutritional supplement ProArgi-9 Plus.  Dr. Joe has used this product on over 6,000 patients.  The American Diabetes Association named him Father of the Year.  Of Dr. Joe’s large high-risk, patient population less than 1% has experienced a stroke or heart attack if they have followed his L-Arginine protocol.  Dr. Joe helped in the design of this study.

Synergy Worldwide – ProArgi-9 Plus is manufactured and distributed by Synergy WorldWide.  They donated the product for this study but didn’t underwrite any of the costs for the study so that they could remain neutral in the study design and results.

Dan Swindell – Dan helped bring all the parties together and helped to facilitate some of the logistics of this study.  He has an intimate knowledge of the study and its results.

Click Here For an Audio Clip as Dan Swindell Provides Additional Details About This Groundbreaking Heart Disease Study

Angelo Cici – Angelo was a patient at the High Desert Heart Institute who was invited to participate in this study because of significant cardiovascular issues.  Angelo worked for Litton Industries as a Director of Product Support that oversaw 100 subsidiary companies.  On December 20, 2008 he experienced a massive heart failure with simultaneous renal failure, congestive heart failure and a pacemaker failure. His life was saved in the emergency room but then he spent the next several weeks in and out of the hospital in an effort to stabilize his health.  As Angelo describes it, “I was so weak I couldn’t even open a bottle of water by myself and I had decided, I had had enough.  I told the nurses I wanted all the IV’s removed and I just wanted to go home and die.” Needless to say Angelo didn’t die and he feels “like I’m 40 years old again!”

Click Here For an Audio Clip of Angelo as He Shares His Powerful & Compelling Life-Changing Testimony

Dr. Louis Ignarro – Dr. Ignarro did not participate in this study but his Nobel Prize winning research is at the heart of this study.  In 1998 Dr. Ignarro shared the Nobel Prize in Medicine with two other American scientists for the discovery of Nitric Oxide and how it is the master signaling molecule for the cardiovascular system. In 2008, the American Heart Association selected Dr. Ignarro as a 2008 Distinguished Scientist.  Dr. Ignarro firmly believes that the proper use of Nitric Oxide can significantly improve the health of most cells and make a major impact on reducing the risk of heart disease.

Click Here to View the American Health Journal’s Video on Dr. Ignarro’s Work on Nitric Oxide

Audio clips About This Study!

Landmark Heart Disease Study – This features an audio of Dan SwinDell interviewing Dr. Siva and Dan Austin on the results of this life changing L-Arginine and Nitric Oxide protocol.

Angelo Cici’s Heart Disease Testimony – This is the story of Angelo Cici and how he went from near death to feeling like he’s in his 40’s again.  It features an audio of Dan SwinDell interviewing Angelo as he shares his compelling testimony!

Ground Breaking Heart Disease Study – This features an audio interview with Dan SwinDell as he provides further details about the design of this study, the exact protocol used for taking ProArgi-9 Plus, and some general trending statements about the results of this study.

High Desert Heart Institute – Nurses Interview Video – This video interview with several of the nurses from the High Desert Heart Institute study provides fascinating insights into this groundbreaking human clinical trial and the remarkable success ProArgi-9 Plus had on its patients.

Angelo Cici’s Video InterviewPart 1 Part 2 This contains a fascinating 2-part interview with Angelo Cici who was one of the participants of the groundbreaking High Desert Heart Institute study and how ProArgi-9 Plus transformed his cardiovascular health.

Additional Research Resources

Endothelial Cells: The Heart of Cardiovascular Health – This page provides you with a great overview of how important your endothelial cells are for cardiovascular health as well as health in general.  It is the Endothelial cells that convert L-Arginine into Nitric Oxide which is the master signaling molecule for the cardiovascular system.

No More Heart Disease Series – This  contains three excellently done videos that will help you understand both the severity of heart disease and the potential for a remarkable reversal to the devastating effects of this disease.

Nobel Prize Laureate – Dr. Louis Ignarro – This contains the 30 minute feature on Dr. Ignarro and his work with Nitric Oxide.  It was produced by the American Health Journal and placed on YouTube in three segments.  This post brings all three video segments together so that you can hear directly from Dr. Ignarro about his Nobel Prize winning research in the area of Nitric Oxide.  You will come to understand how passionately Dr. Ignarro believes that proper Nitric Oxide production can both prevent as well as reverse cardiovascular disease.

The choice is yours. Choose wisely!

Ted Heims


775 342.5788

The information contained in this blog is for general information purposes only and never as a substitute for professional medical advice or medical exam.  The information contain in this blogging website has not been evaluated by the Food and Drug Administration and should not be used to diagnose, treat, cure or prevent any disease without the supervision of a qualified medical doctor.
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